Approaches

Multielectrode array

We use a multielectrode array to record the activity of thousands of neurons simultaneously.

Imaging

We use super-resolution confocal imaging and state-of-the-art software of image analysis, such as Imaris, Neurolucida and Neuroinfo.

Behavior/Cognition

Most of our studies involve a thorough behavioral analysis. For this purpose, our laboratory uses several tests that allow us to evaluate a wide range of rodent behaviors (Barnes Maze, Fear Conditioning, Novel Object Location, and more).

Pharmacology

We treat rodents with a variety of drugs to examine their effect on cognition and behavior.

Electrophysiology

We use many electrophysiological techniques to study the biology of cognition. Specifically, we use patch-clamp and field recording as our main techniques.

Cell Biology

We study signaling pathways involved in synaptic and cognitive functions

Molecular manipulations

We use different strategies to manipulate the function of molecules in the brain, including pharmacology and gene transfer with viral vectors or plasmids in vitro and in vivo. We also use several lines of transgenic mice.

Morphology

We use intracellular injections of fluorescent dyes (Lucifer Yellow, Alexa 594) in fixed tissue and in certain cases also injection of Biocytine during Patch Clamp recording.

In vivo manipulations

We use viral vectors to express specific proteins in neurons in order to change learning and memory in rodents. This approach allowד us to understand the function of key brain proteins.

Awards & Honors

National Research Council Annual tribute to its scientists
July 2017

National Research Council Annual tribute to its scientists

Sieratzki Prize For Advances in Neuroscience
June 2012

Sieratzki Prize For Advances in Neuroscience

Woman of the year in medicine
June 2016

Woman of the year in medicine

More Awards
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