Discovering New Molecular Mechanisms of Learning & Memory

About Us


Multielectrode array

We use a multielectrode array to record the activity of thousands of neurons simultaneously.


We use super-resolution confocal imaging and state-of-the-art software of image analysis, such as Imaris, Neurolucida and Neuroinfo.


Most of our studies involve a thorough behavioral analysis. For this purpose, our laboratory uses several tests that allow us to evaluate a wide range of rodent behaviors (Barnes Maze, Fear Conditioning, Novel Object Location, and more).

More Approaches

Latest Publications

Interplay between hippocampal TACR3 and systemic testosterone in regulating anxiety-associated synaptic plasticity

Tachykinin receptor 3 (TACR3) is a member of the tachykinin receptor family and falls within the rhodopsin subfamily. As a G protein-coupled receptor, it responds to neurokinin B (NKB), its high-affinity ligand. Dysfunctional TACR3 has been associated with pubertal failure and anxiety, yet the mechanisms underlying this remain unclear. Hence,...

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Striatal synaptic bioenergetic and autophagic decline in premotor experimental parkinsonism

Synaptic impairment might precede neuronal degeneration in Parkinson’s disease. However, the intimate mechanisms altering synaptic function by the accumulation of presynaptic α-synuclein in striatal dopaminergic terminals before dopaminergic death occurs, have not been elucidated. Our aim is to unravel the sequence of synaptic functional and structural changes preceding the symptomatic...

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Aberrant Synaptic PTEN in Symptomatic Alzheimer’s Patients May Link Synaptic Depression to Network Failure

In Alzheimer’s disease (AD), Amyloid β (Aβ) impairs synaptic function by inhibiting long-term potentiation (LTP), and by facilitating long-term depression (LTD). There is now evidence from AD models that Aβ provokes this shift toward synaptic depression by triggering the access to and accumulation of PTEN in the postsynaptic terminal of...

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