Recent Publications


  1. Knafo et al., “PTEN Recruitment Controls Synaptic and Cognitive Function in Alzheimer’s Models”. Nature Neuroscience, doi: 10.1038/nn.4225, 2016.Corresponding Author.  *Commentary, Nature Neuroscience, Targeting PTEN interaction to treat Alzheimer’s. S. Frere & I. Slutsky. 2016, 19(3): 416-418.  *Editor’s Choice, Science Signaling, PTEN contributes to Alzheimer’s disease. 2016, 9(417): ec45-ec45.

  2. Draffin  J, Knafo S* and Heneka M* Alzheimer's Disease and Mechanism-Based Attempts to Enhance Cognition. Book Chapter in Cognitive Enhancement: Pharmacologic, Environmental  and Genetic Factors. Editors: Shira Knafo and Cesar Venero. Editorial: Elsevier.  (2015). Editors: Shira Knafo  and César Venero.

  3. Sanz-García, A., Knafo, S., Pereda-Pérez, I., Esteban, J. A., Venero, C., and Armario, A. Administration of the TrkB receptor agonist 7,8-dihydroxyflavone prevents traumatic stress-induced spatial memory deficits and changes in synaptic plasticity. Hippocampus, 26:1179–1188, 2016

  4. Pérez-Cañamás A., Sarroca S., Melero C., Porquet D., Sansa J., Knafo S., Esteban JA, Sanfeliu C, Ledesma MD. Plant sterol enriched diet prevents cholesterol loss-induced memory deficits in senescence-accelerated mice. Neurobiology of Aging, 48 (1-12), 2016

  5. Mellström, B., A. Kastanauskaite, S. Knafo, P. Gonzalez, X. M. Dopazo, A. Ruiz-Nuño, J. G. R. Jefferys, M. Zhuo, T. V. P. Bliss, J. R. Naranjo and J. DeFelipe Specific cytoarchitectureal changes in hippocampal subareas in daDREAM mice. Molecular Brain, 2016, 9(1): 1-12.

  6. Veljko D, Venero C  and  Knafo S*, What Is Cognitive Enhancement? Book Chapter in Cognitive Enhancement: Pharmacologic, Environmental  and Genetic Factors.Editors: Shira Knafo  and Cesar Venero. Editorial: Elsevier.(2015). Editors: Shira Knafo and César Venero. *Corresponding Author.

  7. Knafo S* and Esteban JA*, Molecular Mechanisms of Drug-Induced Cognitive Enhancement. Book Chapter in Cognitive Enhancement: Pharmacologic, Environmental  and Genetic Factors. Editors: Shira Knafo and Cesar Venero. Editorial: Elsevier. (2015). Editors: Shira Knafo  and César Venero. *Corresponding Author.
  8. Mellström B1, Sahún I, Ruiz-Nuño A, Murtra P, Gomez-Villafuertes R, Savignac M, Oliveros JC, Gonzalez P, Kastanauskaite A, Knafo S, Zhuo M, Higuera-Matas A, Errington ML, Maldonado R, DeFelipe J, Jefferys JG, Bliss TV, Dierssen M, Naranjo JR. DREAM controls the on/off switch of specific activity-dependent transcription pathways. Mol Cell Biol. 2014 Mar;34(5):877-87. doi: 10.1128/MCB.00360-13.
  9. Knafo S: Amygdala In Alzheimer's Disease. Book Chapter in "The Amygdala - A Discrete Multitasking Manager". Publisher: In Tech, December 2012. 
  10. Jurado S§ and Knafo S§: Microscale AMPAR Reorganization and Dynamics of the Postsynaptic Density. The Journal of Neuroscience.  2012;32 7103-7105. §Corresponding authors
  11. Knafo S§  and Esteban JA§: Common Pathways for Growth and for Plasticity. Current Opinion in Neurobiology .Review.2012 Mar 5. §Corresponding authors.  
  12. Knafo S§, Venero C§, Sánchez-Puelles C, Pereda-Peréz I, Franco A, Sandi C, Suárez LM, Solís JM, Alonso-Nanclares L, Martín ED, Merino-Serrais P, Borcel E, Li S, Chen Y, Gonzalez-Soriano J, Berezin V, Bock E, DeFelipe J and Esteban JA§:Facilitation of AMPA receptor synaptic delivery as a molecular mechanism for cognitive enhancement. PLoS Biology. 2012 Feb;10(2):e1001262. §Corresponding authors. This paper was reviewed in Nature Research Highlights
  13. Spires-Jones T & Knafo S§: Spines, Plasticity, and Cognition in Alzheimer´s Model Mice. Review. 2012. Neural Plasticity.  2012:319836 §Corresponding author. 
  14. Franco A*, Knafo S*, Banon-Rodriguez I, Merino-Serrais P, Fernaud-Espinosa I, Nieto M, Garrido JJ, Esteban JA, Wandosell F, Anton IM: WIP Is a Negative Regulator of Neuronal Maturation and Synaptic Activity. Cerebral Cortex2011 Aug 1. *Conjoint 1st authors. 
  15. Merino-Serrais P*, Knafo S*§, Alonso-Nanclares L, Fernaud-Espinosa I, DeFelipe J: Layer-specific alterations to CA1 dendritic spines in a mouse model of Alzheimer's disease. Hippocampus2011, 21:1037-1044. * Conjoint 1st authors.§Corresponding author
  16. Jurado S, Benoist M, Lario A, Knafo S, Petrok CN, Esteban JA: PTEN is recruited to the postsynaptic terminal for NMDA receptor-dependent long-term depression. Embo J . 2010 Aug 18;29(16):2827-40.
  17. Arendt KL, Royo M, Fernandez-Monreal M, Knafo S, Petrok CN, Martens JR, Esteban JA: PIP3 controls synaptic function by maintaining AMPA receptor clustering at the postsynaptic membrane. Nat Neurosci 2010, 13:36-44.
  18. Knafo S§, Venero C, Merino-Serrais P, Fernaud-Espinosa I, Gonzalez-Soriano J, Ferrer I, Santpere G, DeFelipe J§:Morphological alterations to neurons of the amygdala and impaired fear conditioning in a transgenic mouse model of Alzheimer's disease. J Pathol2009, 219:41-51. §Corresponding authors.
  19. Knafo S§, Alonso-Nanclares L, Gonzalez-Soriano J, Merino-Serrais P, Fernaud-Espinosa I, Ferrer I, DeFelipe J:Widespread changes in dendritic spines in a model of Alzheimer's disease. Cereb Cortex2009, 19:586-592.§Corresponding author
  20. Knafo S: Microanatomical changes following odor learning: The search for the structural basis of learning and memory. VDM. Saarbrücken, Germany 2009. Book.